2022 HME Business Handbook: Pain Management
Types of CBD: What's Right For Your Patients?
- By Dorian Knape
- Jun 01, 2022
Baby boomers spend an
average of $100 a month
on pain management, and
research shows they prefer to buy
solutions from healthcare professionals.
The best news of all, those
consumers are the same people
HME providers already see today.
Moreover, working with a reliable
CBD company can provide an
opportunity to meet the demands
of patients wanting alternatives to
narcotics and non-steroidal anti-inflammatory drugs (NSAIDs).
There’s solid data available that
supports this. A study released by
Project CDB in 2019, “Cultivating
Wellness: A Survey on the Who,
What, When, Where and Why
of CBD,” surveyed 3,506 people
with 200 questions aiming to
assess factors such as who uses
CBD, the types of products used,
to the purpose of the use and the
outcomes. The survey uncovered
several very compelling findings:
- Almost two-thirds were over
the age of 44, and roughly 20
percent were over the age of 64.
- Users reported a 60 percent
decrease in pain intensity.
- CBD reduced respondents’ time
to get to sleep from about an
hour to 20 minutes.
- Participants reported waking up
less often — 1.4 times per night
- 92 percent of participants
experienced some relief from
anxiety; 68 percent said their
nervousness was “much better.”
FOUR TYPES OF CBD
There are four primary types of CBD
available on the market today: fullspectrum
CBD, broad-spectrum CBD,
CBD isolate, and water-soluble, nanoamplified CBD isolate plus terpenes.
Full-spectrum and broad-spectrum
CBD are distillate oils that contain
a combination of cannabinoids with
tetrahydrocannabinol (THC), terpenes
and other compounds. Broad-spectrum
removes the majority of THC, but trace
amounts are still embedded in the oil.
THC even in trace amounts is a concern
to many medical professionals due
to possible side effects and adverse
outcomes. The absorption rate for
distillate oil is approximately 6 percent
and requires liver function to be
absorbed in the body.
CBD isolate refers to CBD that is
isolated from THC and the rest of the
compounds in the plant to provide a pure
form of CBD that does not contain even
trace amounts of THC. However, the lack
of additional compounds may limit its
Water-soluble, nano-amplified 99.9
percent CBD isolate plus terpenes is a
refined version of CBD Isolate in which
CBD is isolated and extracted from the
plant. A nano-emulsification process
converts raw crystal isolate powder into
nano water-soluble CBD to increase its
bioavailability. The extracted natural
terpenes are then infused while ensuring
the product contains no THC.
THE BENEFITS OF WATER-SOLUBLE, NANO-AMPLIFIED
99.9 PERCENT CBD
This type’s benefits:
- Purest form of CBD
- No risk of intoxication
- Entourage effect; other chemicals
found in the cannabis plant work with
the CBD to boost its benefit
- Enhanced potency
- Enhanced bioavailability
- Users will not test positive for THC
Nano water-soluble, THC-free, CBD
is engineered to bypass digestive
processes and prevent gastrointestinal
effects and potential drug interactions.
TERPENES SYNERGISTIC EFFECTS
The entourage effect can be
accomplished without involving THC.
Terpenes are believed to amplify the
effects of CBD by playing a role at a
cellular level and interacting with the
ECS receptors, according to “Taming
THC: potential cannabis synergy and
effects,” by GW Pharmaceuticals’ Ethan
Russo (this was published in the British
Journal of Pharmacology in 2011).
The FDA considers some terpenes
to be Generally Recognized as Safe
for food use, provided they are used in
accordance with FDA regulations. For
example, linalool in lavender is used for
relaxation and caryophyllene is often
used for its anti-inflammatory properties.
WHAT TO LOOK FOR IN A CBD COMPANY
As mentioned, partnering with the right
company can help you address patients’
needs. Here’s what to look for:
- Licensed USA farm.
- Third-party full panel testing with
Certificate of Analysis (COA).
- Web-based track and trace system.
- Compliant product labeling.
- Training & education.
- Protocols & guidelines.
- Customized provider online store.
POINTS TO REMEMBER
In a 2019 study conducted by Nakano
et al., nano water-soluble, THC free
CBD delivers greater bioavailability
than conventional CBD oil with the
- More complete absorption; not
dependent on liver function
- Faster onset of action; maximized
- Accommodates more specific
- Requires lower dose to be effective
- Minimizes potential drug interactions
and side effects.
To learn more about BioNan-X
Medical formulations for the healthcare
marketplace, visit online at
This article originally appeared in the May/Jun 2022 issue of HME Business.
Dorian Knape is the founder and CEO of BioNan-X Medical, which manufactures targeted CBD formulations for healthcare professionals. For further discussion, contact firstname.lastname@example.org.